6-(2-Chloro-5-fluoropyrimidin-4-yl)-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

Applications

6-(2-Chloro-5-fluoropyrimidin-4-yl)-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole This compound is a heterocyclic organic intermediate primarily used in pharmaceutical research and the synthesis of active pharmaceutical ingredients (APIs). It is not typically marketed as a finished drug, but rather as a drug discovery and manufacturing intermediate. Molecular Information Property Value Molecular Formula C15H14ClF2N3 Molecular Weight Approximately 309.72 g/mol Functional Groups Benzimidazole, Pyrimidine, Fluorinated Aromatic Ring, Chloropyrimidine Ring System Benzimidazole + Pyrimidine Structural Features The molecule contains: Benzimidazole nucleus Fluorinated aromatic ring Chlorofluoropyrimidine moiety Isopropyl substituent Methyl substituent These structural features improve: Biological activity Binding affinity Metabolic stability Lipophilicity Selectivity toward biological targets Applications Pharmaceutical Industry Used as an intermediate for developing: Anticancer drugs Kinase inhibitors Targeted therapies Anti-inflammatory agents Immunology drugs Precision medicines Medicinal Chemistry Researchers use this intermediate for: Structure Activity Relationship (SAR) studies Lead optimization Library synthesis Analog development